Yusof, Y. A. Ginger extract Zingiber officinale has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. Clinics. They can irritate your stomach. You might try a heating pad to ease belly pain. Chamomile or peppermint tea may help with gas. Be sure to drink plenty of clear fluids so your body has enough water. Moran H, Hanna DB, Ansell BM et al. Naproxen in juvenile chronic polyarthritis. Ann Rheum Dis. Surgery. Although sometimes surgery is clearly necessary to relieve a problem that is causing pain, it is often a treatment of last resort. If pain has not responded to any other treatment, surgery on certain nerves may offer relief and allow you to resume normal activities.
If renal function declines or renal failure occurs, prompt discontinuation of NSAID therapy will usually lead to recovery to the pretreatment state. NSAIDs are generally not recommended for patients with advanced renal disease due to the lack of information from controlled clinical studies regarding their use in such patients. FDA recommends that parents and caregivers adhere to dosage instructions and warnings on the product labeling that accompanies the preparation and consult a clinician about any concerns. LONG-TERM ADMINISTRATION OF NSAIDS HAS RESULTED IN RENAL PAPILLARY NECROSIS AND OTHER RENAL INJURY.
Pillai AK, Sharma KK, Gupta YK, et al. Anti-emetic effect of ginger powder versus placebo as an add-on therapy in children and young adults receiving high emetogenic chemotherapy. Pediatr Blood Cancer. Bunea R, El Farrah K, Deutsch L. Evaluation of the effects of Neptune Krill Oil on the clinical course of hyperlipidemia. De, Nucci G. Clinical toxicology study of an herbal medicinal extract of Paullinia cupana, Trichilia catigua, Ptychopetalum olacoides and Zingiber officinale Catuama in healthy volunteers. Phytother. Cady RK, Schreiber CP, Beach ME, et al. Gelstat Migraine sublingually administered feverfew and ginger compound for acute treatment of migraine when administered during the mild pain phase. Med Sci Monit.
TO MINIMIZE THE POTENTIAL RISK FOR AN ADVERSE CV EVENT IN NSAID-TREATED PATIENTS, USE THE LOWEST EFFECTIVE DOSE FOR THE SHORTEST DURATION POSSIBLE. PHYSICIANS AND PATIENTS SHOULD REMAIN ALERT FOR THE DEVELOPMENT OF SUCH EVENTS, THROUGHOUT THE ENTIRE TREATMENT COURSE, EVEN IN THE ABSENCE OF PREVIOUS CV SYMPTOMS. PATIENTS SHOULD BE INFORMED ABOUT THE SYMPTOMS OF SERIOUS CV EVENTS AND THE STEPS TO TAKE IF THEY OCCUR. Schechter JO. Treatment of disequilibrium and nausea in the SRI discontinuation syndrome. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Some medications for high blood pressure and heart disease include nifedipine Adalat, Procardia verapamil Calan, Isoptin, Verelan diltiazem Cardizem isradipine DynaCirc felodipine Plendil amlodipine Norvasc and others. If changing from one strength to another or one dosage form to another, be aware that different dose strengths and formulations are not necessarily bioequivalent. The risk of infant exposure to codeine and morphine through breast milk should be weighed against the benefits of breastfeeding for both the mother and baby. Caution should be exercised when codeine is administered to a nursing woman. If a codeine-containing product is selected, the lowest dose should be prescribed for the shortest period of time to achieve the desired clinical effect. Mothers using codeine should be informed about when to seek immediate medical care and how to identify the signs and symptoms of neonatal toxicity, such as drowsiness or sedation, difficulty breastfeeding, breathing difficulties, and decreased tone, in their baby. Nursing mothers who are ultra-rapid metabolizers may also experience overdose symptoms such as extreme sleepiness, confusion or shallow breathing. Your symptoms keep getting worse. Naproxen may also be used for purposes not listed in this medication guide. Smith, M. L. Inhibition of human pathogenic fungi by ethnobotanically selected plant extracts. Onyenekwe, P. C. Assessment of oleoresin and gingerol contents in gamma irradiated ginger rhizomes. If you use this medicine long-term, you may need frequent medical tests. P450 isoenzyme 2D6 or high morphine concentrations. Deaths have also occurred in nursing infants who were exposed to high levels of morphine in breast milk because their mothers were ultra-rapid metabolizers of codeine. Cruzan S US Department of Health and Human Services. FDA proposes alcohol warning for all OTC pain relievers. Rockville, MD; 1997 Nov 14. Press release No. P97-37. Food and Drug Administration. Cough and cold medications in children less than two years of age. Rockville, MD; 2007 Jan 12. From FDA website. Chen, L. D. Gypenoside induces apoptosis in human Hep3B and HA22T tumour cells.
Naprosyn, EC-Naprosyn, ANAPROX, ANAPROX DS and Naprosyn Suspension, like other NSAIDs, may cause serious CV side effects, such as MI or stroke, which may result in hospitalization and even death. Although serious CV events can occur without warning symptoms, patients should be alert for the signs and symptoms of chest pain, shortness of breath, weakness, slurring of speech, and should ask for medical advice when observing any indicative sign or symptoms. What is the treatment for rheumatoid arthritis? Wilmington, DE; 2010 Apr. Before taking Colcrys, tell your doctor if you have liver or kidney disease, heart disease, a stomach ulcer, ulcerative colitis, Crohn's disease, intestinal bleeding, or any other severe gastrointestinal disorder. Butalbital, acetaminophen, caffeine, and codeine phosphate capsules should be prescribed with caution in certain special-risk patients such as the elderly or debilitated, and those with severe impairment of renal or hepatic function, head injuries, elevated intracranial pressure, acute abdominal conditions, hypothyroidism, urethral stricture, Addison's disease, or prostatic hypertrophy. Singh G, Triadafilopoulos G. Epidemiology of NSAID induced gastrointestinal complications. J Rheumatol. Sampalis F, Bunea R, Pelland MF, et al. Evaluation of the effects of Neptune Krill Oil on the management of premenstrual syndrome and dysmenorrhea. Dosage adjustment may be needed if high doses required. 225 Consider reduced initial dosage. 225 Use lowest effective dosage. Anon. Drugs for rheumatoid arthritis. Med Lett Drugs Ther. Avoid drinking alcohol. It may increase your risk of stomach bleeding. KG GIVEN IN 2 DIVIDED DOSES. ONE-HALF OF THE 250 MG TABLET WILL BE NEEDED FOR DOSING LOWER-WEIGHT CHILDREN. DOSING WITH Naproxen Tablets IS NOT APPROPRIATE FOR CHILDREN WEIGHING LESS THAN 25 KILOGRAMS. Naproxen as Naprosyn Suspension is recommended for juvenile rheumatoid arthritis in order to obtain the maximum dosage flexibility based on the patient's weight. albuterol
Naprosyn, EC-Naprosyn, ANAPROX, ANAPROX DS and Naprosyn Suspension should be discontinued. F. Dispense in light-resistant containers. Shake gently before use. EC-Naprosyn naproxen delayed-release tablets is available as enteric-coated white tablets containing 375 mg of naproxen and 500 mg of naproxen for oral administration. The inactive ingredients are croscarmellose sodium, povidone and magnesium stearate. The enteric coating dispersion contains methacrylic acid copolymer, talc, triethyl citrate, sodium hydroxide and purified water. Kurumbail RG, Stevens AM, Gierse JK et al. Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature. 1996; 384-644-8. Kruth P, Brosi E, Fux R, et al. Ginger-associated overanticoagulation by phenprocoumon. To treat a gout attack, for best results take Colcrys at the first sign of the attack. HIV or AIDS medicine - atazanavir, darunavir, fosamprenavir, indinavir, lopinavir, nelfinavir, ritonavir, or saquinavir. brese.info oxytrol
Riendeau D, Charleson S, Cromlish W et al. Comparison of the cyclooxygenase-1 inhibitory properties of nonsteroidal anti-inflammatory drugs NSAIDs and selective COX-2 inhibitors, using sensitive microsomal and platelet assays. Can J Physiol Pharmacol. Store Naprosyn at room temperature, between 59 and 86 degrees F 15 and 30 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Naprosyn out of the reach of children and away from pets. Codeine may increase serum amylase levels. Martinez, L. D. Non-chromatographic screening method for the determination of mercury species. Application to the monitoring of mercury levels in Antarctic samples. Long-term administration of NSAIDs has resulted in renal papillary necrosis and other renal injury. Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion. In these patients, administration of a nonsteroidal anti-inflammatory drug may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Patients at greatest risk of this reaction are those with impaired renal function, hypovolemia, heart failure, liver dysfunction, salt depletion, those taking diuretics and angiotensin converting enzyme ACE inhibitors or angiotensin receptor blockers ARBs and the elderly. Thomson M, Corbin R, Leung L. Effects of ginger for nausea and vomiting in early pregnancy: a meta-analysis. MONITOR BLOOD PRESSURE BP DURING THE INITIATION OF NSAID TREATMENT AND THROUGHOUT THE COURSE OF THERAPY. Ginger might slow blood clotting. Taking ginger along with medications that also slow clotting might increase the chances of bruising and bleeding. Some medical conditions may interact with Naprosyn. Apply soothing lotions that contain aloe vera to burned areas to relieve pain and swelling. Applying to the burned area also may help.
Elevation. Elevate the injured or sore area on pillows while applying ice and anytime you are sitting or lying down. Try to keep the area at or above the level of your to help minimize swelling. Bleeding disorders: Jiaogulan may slow blood clotting. There is a concern that it might make bleeding disorders worse. Surgery: Jiaogulan might slow blood clotting. There is some concern that it might increase the risk of bleeding during and after surgery. Stop using jiaogulan at least 2 weeks before a scheduled surgery. Li, Y. A 35-day gavage safety assessment of ginger in rats. Regul. CV events and the steps to take if they occur. Monitor liver function periodically during long-term therapy. Ferrando, A. A. Eight weeks of supplementation with a multi-ingredient weight loss product enhances body composition, reduces hip and waist girth, and increases energy levels in overweight men and women. Do not put ice or butter on the burned area, because these measures do not help and can damage the skin tissue. The electrical system of the heart consists of the SA node sinoatrial node the AV node and special tissues in the atria and the ventricles that conduct the current. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? It helps to reduce leaking of urine, feeling of needing to urinate right away, and frequent trips to the bathroom. Wang, N. Purification and characterization of trypsin-like enzymes from North Pacific krill Euphausia pacifica. Biotechnol. Ann Ital Med Int. What are tips for living with rheumatoid arthritis? Your doctor might suggest that you rest in bed. Bed rest is fine for a short period of time, but don't stay off your feet for longer than 1 or 2 days. Zahmatkash M, Vafaeenasab MR. Comparing analgesic effects of a topical herbal mixed medicine with salicylate in patients with knee osteoarthritis. Pak J Biol Sci. chloramphenicol
Extent of absorption similar for commercially available formulations; peak plasma concentrations also similar, although about 36% lower with conventional tablets containing naproxen sodium 500 mg and sumatriptan than with conventional naproxen sodium 550-mg tablets. Patients should be informed of the warning signs and symptoms of hepatotoxicity eg, nausea, fatigue, lethargy, pruritus, jaundice, right upper quadrant tenderness, and "flu-like" symptoms. If these occur, patients should be instructed to stop therapy and seek immediate medical therapy. If your symptoms do not improve or if they become worse, check with your doctor. All registered trademarks in this document are the property of their respective owners. Home treatment may help relieve pain, swelling, and stiffness related to a neck problem. BLEEDING. FOR SUCH PATIENTS, AS WELL AS THOSE WITH ACTIVE GI BLEEDING, CONSIDER ALTERNATE THERAPIES OTHER THAN NSAIDS. Lumbar laminotomy. Sometimes your surgeon will also need to remove a small piece of bone called the lamina from the vertebra. The lamina forms a protective cover over your spinal cord. Removing part or all of it helps the surgeon access your herniated disk. Some exercises can help improve the symptoms of a herniated disc. A physical therapist can teach you which ones strengthen the muscles that support your back. Elimination of butalbital is primarily via the kidney 59% to 88% of the dose as unchanged drug or metabolites. The plasma half-life is about 35 hours. buy mirtazapine in store
COLLABORATION META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS DEMONSTRATED AN APPROXIMATELY TWO-FOLD INCREASE IN HOSPITALIZATION FOR HEART FAILURE IN COX-2 SELECTIVE-TREATED PATIENTS AND NONSELECTIVE NSAID-TREATED PATIENTS COMPARED TO PLACEBO-TREATED PATIENTS. IN A DANISH NATIONAL REGISTRY STUDY OF PATIENTS WITH HEART FAILURE, NSAID USE INCREASED THE RISK OF MI, HOSPITALIZATION FOR HEART FAILURE, AND DEATH. ADDITIONALLY, FLUID RETENTION AND EDEMA HAVE BEEN OBSERVED IN SOME PATIENTS TREATED WITH NSAIDS. Vicoprofen contains the same dose of ibuprofen as over-the-counter OTC NSAID, and is usually used for less than 10 days to treat pain. The OTC NSAID label warns that long term continuous use may increase the risk of heart attack or stroke. See, L. C. The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver disease. OR ADVERSE EVENTS. A LOWER DOSE SHOULD BE CONSIDERED IN PATIENTS WITH RENAL OR HEPATIC IMPAIRMENT OR IN ELDERLY PATIENTS SEE WARNINGS; HEPATOTOXICITY, AND RENAL TOXICITY AND HYPERKALEMIA, AND PRECAUTIONS; GERIATRIC USE. Gingerol inhibits nitric oxide synthesis in activated J774. Inhibits cyclooxygenase-1 COX-1 and COX-2. Alcohol hangover. Early research suggests that taking a combination of ginger, pith of Citrus tangerine, and brown sugar before drinking decreases symptoms of alcohol hangovers, including nausea, vomiting, and diarrhea. Do not bandage or wrap the affected area unless directed otherwise by your doctor. Speeding up labor. Early evidence suggests that bathing in water containing ginger oil does not shorten the length of labor. Codeine can produce drug dependence of the morphine type and, therefore, has the potential for being abused. Psychological dependence, physical dependence, and tolerance may develop upon repeated administration and it should be prescribed and administered with the same degree of caution appropriate to the use of other oral narcotic medications. Leelakusolvong, S. Effect of ginger on lower esophageal sphincter pressure.
F in well-closed containers; dispense in light-resistant containers. Rotterdam Study. Neurobiol Aging. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Do not stop using Colcrys unless your doctor tells you to, even if you feel fine. NSAIDs have a greater than 10-fold increased risk for developing a GI bleed compared to patients with neither of these risk factors. Other factors that increase the risk for GI bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status. Most spontaneous reports of fatal GI events are in elderly or debilitated patients and therefore, special care should be taken in treating this population. To minimize the potential risk for an adverse GI event in patients treated with an NSAID, the lowest effective dose should be used for the shortest possible duration. Patients and physicians should remain alert for signs and symptoms of GI ulceration and bleeding during NSAID therapy and promptly initiate additional evaluation and treatment if a serious GI adverse event is suspected. This should include discontinuation of the NSAID until a serious GI adverse event is ruled out. For high risk patients, alternate therapies that do not involve NSAIDs should be considered. Kearney PM, Baigent C, Godwin J et al. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Timmermann, B. N. Fresh organically grown ginger Zingiber officinale: composition and effects on LPS-induced PGE2 production. Apply a generous amount to the affected area. Gently rub the medicine into the skin until it is completely absorbed. Also inform your doctor so that these medications are not prescribed for you. If you have any questions whether a certain medication could trigger your asthma, seek advice from your provider. If you have a sun allergy, your treatment must always begin with the strategies described in the Prevention section. These will reduce your sun exposure and prevent your symptoms from worsening. But most problems are minor and will clear up with home treatment and time. Simple home treatment measures, such as increasing your fluid intake to prevent and using a humidifier inside your home, can relieve many problems. In the presence of head injury or other intracranial lesions, the respiratory depressant effects of codeine and other narcotics may be markedly enhanced, as well as their capacity for elevating cerebrospinal fluid pressure. Narcotics also produce other CNS depressant effects, such as drowsiness, that may further obscure the clinical course of the patients with head injuries. how much does minocycline in canada
AFTER THE FIRST YEAR POST-MI, THE INCREASED RELATIVE RISK OF DEATH IN NSAID USERS PERSISTED OVER AT LEAST THE NEXT FOUR YEARS OF FOLLOW-UP. NSAIDs inhibit platelet aggregation and have been shown to prolong bleeding time in some patients. Unlike aspirin, their effect on platelet function is quantitatively less, of shorter duration, and reversible. Patients receiving either Naprosyn, EC-Naprosyn, ANAPROX, ANAPROX DS or Naprosyn Suspension who may be adversely affected by alterations in platelet function, such as those with coagulation disorders or patients receiving anticoagulants, should be carefully monitored. Apply petroleum jelly, such as Vaseline, to ease the cracking and dryness of a lip sore. Patients with initial hemoglobin values of 10 g or less who are to receive long-term therapy should have hemoglobin values determined periodically. Administer orally twice daily. Administer at least 30 minutes before meals; patient may use antacids during therapy. You also can do things to make stomach pain less likely. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. When a first-degree burn or minor second-degree burn is 2 to 3 days old, using the juice from an aloe leaf can help the burn heal and feel better. Applying the aloe juice may sting at first contact. order dramamine online mastercard europe
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide. If an object is over the dark center pupil of the eye or over the colored part iris of the eye, you may try to gently it out with water. If the object does not come out with flushing, put on dark glasses, and call your doctor. Do not put any pressure on the eye. Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Ageel, A. M. Studies on herbal aphrodisiacs used in Arab system of medicine. NSAIDs. In: Tatro DS, Olin BR, Hebel SK eds. Drug interaction facts. If you think a might be the cause of your symptoms, call or other emergency services immediately. Maximum 2 doses total sumatriptan dosage of 170 mg in any 24-hour period. NSAIDs have produced an elevation of plasma lithium levels and a reduction in renal lithium clearance. The mean minimum lithium concentration increased 15% and the renal clearance was decreased by approximately 20%. These effects have been attributed to inhibition of renal prostaglandin synthesis by the NSAID. Thus, when NSAIDs and lithium are administered concurrently, subjects should be observed carefully for signs of lithium toxicity. Risk of serious skin reactions. 225 Risk of anaphylactoid and other sensitivity reactions. Kusano, S. Enhancement of insulin sensitivity in adipocytes by ginger. Place a towel over the cold or heat pack before applying it to the skin. If your pain lasts longer than a few days or it gets worse, call a doctor.
When used for self-medication, importance of reviewing the warning information provided by the manufacturer. Do not purchase colchicine on the Internet or from vendors outside of the United States. Using this medication improperly or without the advice of a doctor can result in serious side effects or death. Naproxen is an odorless, white to off-white crystalline substance. Coxib and traditional NSAID Trialists' CNT Collaboration, Bhala N, Emberson J et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet. AVOID THE USE OF NAPROXEN IN PATIENTS WITH SEVERE HEART FAILURE UNLESS THE BENEFITS ARE EXPECTED TO OUTWEIGH THE RISK OF WORSENING HEART FAILURE. IF NAPROXEN IS USED IN PATIENTS WITH SEVERE HEART FAILURE, MONITOR PATIENTS FOR SIGNS OF WORSENING HEART FAILURE. Some people have no signs or symptoms. Such tasks should be avoided while taking butalbital, acetaminophen, caffeine, and codeine phosphate capsules. Limit the amount of alcohol you drink. Don't drink more than 2 drinks a day if you are a man, or 1 alcoholic drink a day if you are a woman. droxia tablets pharmacy
Be safe with medicines. Read and follow all instructions on the label. Chadwick, L. R. In vitro susceptibility of Helicobacter pylori to botanical extracts used traditionally for the treatment of gastrointestinal disorders. Phytother. This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation forming of a hole. These conditions can be fatal and can occur without warning while you are taking naproxen, especially in older adults. Take an over-the-counter pain medicines like , or , . These medicines can help relieve your pain and bring down swelling. AVOID ADMINISTRATION OF MORE THAN ONE NSAID AT A TIME. If you do not need emergency medical treatment for your chest pain or angina, before reporting your symptoms to your doctor. Your and rhythm at the time of your chest pain may help your doctor evaluate your symptoms. The terminal half-life appears to be similar in pediatric and adult patients. Pharmacokinetic studies of naproxen were not performed in pediatric patients younger than 5 years of age. Pharmacokinetic parameters appear to be similar following administration of naproxen suspension or tablets in pediatric patients. See the end of this Medication Guide for a list of prescription NSAID medicines. Warm or cool mist may help you feel more comfortable by soothing the swollen air passages. It may also relieve hoarseness. But don't let your room become uncomfortably cold or very damp. Tandy S, Chung RW, Wat E, et al. Dietary krill oil supplementation reduces hepatic steatosis, glycemia, and hypercholesterolemia in high-fat-fed mice. Yamahara J, Rong HQ, Iwamoto M, and et al. Active components of ginger exhibiting anti-serotonergic action. Naproxen is highly bound to plasma albumin; it thus has a theoretical potential for interaction with other albumin-bound drugs such as coumarin-type anticoagulants, sulphonylureas, hydantoins, other NSAIDs, and aspirin. Practice good posture. Avoid slouching or a head-forward posture. Jiaogulan is POSSIBLY SAFE when taken by mouth short-term up to 4 months. It can cause some side effects such as severe nausea and increased bowel movements. Advise patients that some people have a genetic variation that results in codeine changing into morphine more rapidly and completely than other people. Most people are unaware of whether they are an ultra-rapid codeine metabolizer or not. These higher-than-normal levels of morphine in the blood may lead to life-threatening or fatal respiratory depression or signs of overdose such as extreme sleepiness, confusion, or shallow breathing. simvastatin
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These medicines may not be safe for young children or for people who have certain health problems. Before you use them, check the label. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Colcrys only for the indication prescribed. Consider taking nonprescription medicine for your symptoms. Be safe with medicines. Al-Amin ZM, Thomson M, Al-Qattan KK, et al. Anti-diabetic and hypolipidaemic properties of ginger Zingiber officinale in streptozotocin-induced diabetic rats. Br J Nutr.
More evidence is needed to rate ginger for these uses. Hsiao, W. L. Three dammarane-type saponins from Gynostemma pentaphyllum. Bliddal H, Rosetzsky A, Schlichting P, et al. A randomized, placebo-controlled, cross-over study of ginger extracts and ibuprofen in osteoarthritis. Cover the burn with a clean, dry cloth to reduce the risk of infection.
You should not use naproxen if you are allergic to it, or if you have a history of allergic reaction to aspirin or other NSAIDs. There isn't strong evidence that heat or ice helps. But you can try using them to see if they help you. CFR Part 201. Final rule.
Whiplash is characterized by a collection of symptoms that occur following damage to the neck. In whiplash, the intervertebral joints located between vertebrae discs, and ligaments, cervical muscles, and nerve roots may become damaged. What Causes Whiplash? Naprosyn should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed. Do not use this medicine without a doctor's advice if you are pregnant. When sleeping, place a small support pillow under your neck, not under your head. Ask a doctor or pharmacist before using any cold, allergy, or pain medication. Many medicines available over the counter contain aspirin or other medicines similar to naproxen such as ibuprofen or ketoprofen. Taking certain products together can cause you to get too much of this type of medication. Check the label to see if a medicine contains naproxen, aspirin, ibuprofen, or ketoprofen.